About The Need 

Many of the complications related to prolonged ventilation are related to inappropriate handling of endotracheal tube (ETT) cuff. This article reviews the possible complications associated with the ETT cuff, and the landmark development made in that field. The article challenges the present paradigm of cuff use and reviews the current clinical practice in that area.

Endotracheal tube cuff-small important part of a big issue

Shai Efrati, Israel Deutsch & Gabriel M. Gurman

Ventilator-associated pneumonia (VAP) is associated with significant morbidity, mortality and healthcare costs. Most of the cost data that are available relate to general intensive care patients in privately remunerated institutions. This study assessed the cost of managing VAP in a cardiac intensive care unit (CICU) in the National Health Service (NHS) in the United Kingdom.

Cost of treating Ventilator Associated Pneumonia post cardiac surgery in the National Health Service: results from a propensity-matched cohort study.

Heyman Luckraz , et al.


Clinical Outcome Using The AnapnoGuard Device 

A key component of the perioperative management of lung transplant recipients is the avoidance of airway and pulmonary complications in the immediate postoperative period. The AnapnoGuardTM AG100s (Hospitech Respiration Ltd, Kfar Saba, Israel), a novel endotracheal tube and ventilation management system, holds the potential to assist the care team in attenuating complications related to excessive cuff pressure, subglottic secretions, and endobronchial intubation. In this report, we describe the successful use of the AnapnoGuardTM AG100s system in the postoperative management of a lung transplant recipient.

The Use of a Novel Endotracheal Tube and
Airway Management System to Prevent
Complications in Lung Transplantation

Vivian Hernandez-Torres, Robert Ratzlaff, Mathew Thomas, Tathagat Narula, Archer K. Martin

Prospective, single centre, open-label, randomized, controlled feasibility and safety trial designed to determine the safety and clinical efficacy of an innovative integrated airway system (AnapnoGuard™100 system) that continuously monitors and controls the cuff pressure (Pcuff), while facilitating the aspiration of subglottic secretions (SS).

CO2 driven endotracheal tube cuff control in critically ill patients: A randomized controlled study

Gennaro De Pascale, Massimo Antonelli et al.

Many of the complications of mechanical ventilation are related to inappropriate endotracheal tube (ETT) cuff pressure. The aim of the current study was to evaluate the effectiveness of automatic cuff pressure closed-loop control in patients under prolonged intubation, where presence of carbon dioxide (CO2) in the subglottic space is used as an indicator for leaks.

Optimization of Endotracheal Tube Cuff Pressure by Monitoring CO2 Levels in the Subglottic Space in Mechanically Ventilated Patients: A Randomised Controlled Trial

Shai Efrati ,Gil Bolotin,et al.