Publications
Clinical Outcome Using The AnapnoGuard Device
The
MICROINHALO multicenter randomized
controlled trial
Gennaro De Pascale, et al.
2026
The Use of a Novel Endotracheal Tube and
Airway Management System to Prevent
Complications in Lung Transplantation
Vivian Hernandez-Torres, Robert Ratzlaff, Mathew Thomas, Tathagat Narula, Archer K. Martin
A key component of the perioperative management of lung transplant recipients is the avoidance of airway and pulmonary complications in the immediate postoperative period. The AnapnoGuardTM AG100s (Hospitech Respiration Ltd, Kfar Saba, Israel), a novel endotracheal tube and ventilation management system, holds the potential to assist the care team in attenuating complications related to excessive cuff pressure, subglottic secretions, and endobronchial intubation. In this report, we describe the successful use of the AnapnoGuardTM AG100s system in the postoperative management of a lung transplant recipient.
CO2 driven endotracheal tube cuff control in critically ill patients: A randomized controlled study
Gennaro De Pascale, Massimo Antonelli et al.
Prospective, single centre, open-label, randomized, controlled feasibility and safety trial designed to determine the safety and clinical efficacy of an innovative integrated airway system (AnapnoGuard™100 system) that continuously monitors and controls the cuff pressure (Pcuff), while facilitating the aspiration of subglottic secretions (SS).
Optimization of Endotracheal Tube Cuff Pressure by Monitoring CO2 Levels in the Subglottic Space in Mechanically Ventilated Patients: A Randomised Controlled Trial
Shai Efrati ,Gil Bolotin,et al.
Many of the complications of mechanical ventilation are related to inappropriate endotracheal tube (ETT) cuff pressure. The aim of the current study was to evaluate the effectiveness of automatic cuff pressure closed-loop control in patients under prolonged intubation, where presence of carbon dioxide (CO2) in the subglottic space is used as an indicator for leaks.
CO2 driven endotracheal tube cuff control in critically ill patients: A randomized controlled study
Gennaro De Pascale* , Mariano Alberto Pennisi, Maria Sole Vallecoccia, Giuseppe Bello, Riccardo Maviglia, Luca Montini, Valentina Di Gravio, Salvatore Lucio Cutuli, Giorgio Conti, Massimo Antonelli
Maintaining the endotracheal tube (ETT) cuff appropriately inflated plays a crucial role in the management of incubated patients. Overinflation of the ETT cuff may compromise capil lary perfusion causing ischemic tracheal wall damage, ulcerations and tracheal stenosis. Conversely, suboptimal tracheal sealing, usually associated with Pcuff values below 20 cmH2O, may result in significant fluid leakage around the cuff, which is a crucial risk factor for ventilator associated pneumonia (VAP).